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3:21 am May 19, 2009
| George Glasser
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Saw your statement about apple cider vinegar. I tried it and it worked very fast. personally, I didn’t think it would from my initial research, but from the preponderance of positive, anecdotal evidence, I gave it a shot.
Being an ex investigative, environmental journalist, I wanted to find out why, and like you, couldn’t find any reason at first. However, as I investigated further, it contains malic acid, which apparently neutralizes uric acid.
I also found it curious that absolutely not scientific research has been done with ACV and gout, but interestingly, apples are one of the fruits that have been researched the most for curative properties, and have the highest malic acid content. Apples are also a reccommended food for people suffering with gout.Consequently, it’s reasonable to to state that, ACV would also have high levels of malic acid which may well be more bioavailable than simply eating and digesting a whole apple.
I’ve seen data which states that the malic acid level in fermented apple cider can easily reach 1.5%.
I determined that I have a potassium deficiency, and while the ACV gave me a kick start, I have increased my uptake of potassium.
I think that it is possible that many problems with gout may well be related to potassium deficiency.
Best Regards,
GC Glasser
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7:49 am May 19, 2009
| GoutPal
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| posts 1200 |
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You're absolutely right that no scientific research has been done on ACV and gout. Neither has any research been done on malic acid and gout.
Not surprisingly, this does not stop the less scrupulous ACV vendors claiming that somehow the malic acid in ACV neutralizes uric acid. Neither does it stop lazy journalists and website publishers repeating the claim. A normal Google search sees this claim repeated on hundreds of sites, but I have yet to see a reference to any proof. I certainly cannot find any link using scientific search resources.
There may be some uncharted mechanisms by which ACV can help reduce inflammation or somehow (by placebo?) help gout sufferers. So perhaps no harm done?
Except that it distracts gout sufferers from the real issue – get blood checked, and find a way to keep uric acid below 6mg/dL.
Speaking of which, distraction is a recognized technique for managing pain. What better way of distraction than GC Glasser's intriguingly hypnotic website. (or is that hypnotically intriguing?)
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Unless replying to specific points in this topic, please start a new topic. See new topic link above, or gout forum guidelines. Current gout status in my profile.
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8:18 am May 19, 2009
| zip2play
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Post edited 1:34 pm – May 19, 2009 by zip2play
Just to be chemically precise, there is no way to neutralize an acid with another acid. To neutralize an acid one needs to use a base, an ALKALINE substance.
Yes, the kidney's alility to retain or release uric acid is closely related to it's handling of poassium both are influenced by handling of sodium. It's a delicate dance and helps explain why people can precipitate a gout attack by using thiazide diuretics which cause elimination of soidium and for balance an elimination of potassium and to balance BOTH, a retention of urate ion. But this electrolyte dance is not a simple matter. Perhaps increase of potassium is wise since historically we get less and less of it while we get more and more sodium.
I find that any discussion of cider vinegar to cause MEGO (my eyes glaze over) because I have read over the years about its ability to cure amost EVERYTHING. My experience is that any such miracle usually cures NOTHING, except perhaps poor apple sales. The cider vinegar people have a GOOD ad-campaign going for them.
The answer to any of these “cures” is a simple study with half a large population taking the miracle stuff and half not. The ABSENCE of these studies should breed a healthy skepticism.
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2:56 pm June 22, 2009
| George Glasser
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Actually, it isn't any magical properties in ACV, it's the plain old acetic acid that does the trick. Acetic acid is absorbed through the stomach as ionic acetate – not as an acid per-se – and oxidizes to a bicarbonate which raises the blood pH.
Potassium acetate is used for gout treatment. When it passes through the stomach lining into the blood, it converts to potassium carbonate, raises the blood pH and the alkaline salts excreted by the kidney render the urine less acid. “It is a marked diuretic, increasing the amount of urine and the solids of the urine without irritation of the kidney,” American Medical Association – “A Handbook of Usefu Drugs.”
Sodium acetate can also be used, but it causes stomach upset in some people – it would convert to bicarbonate of soda.
Potassium citrate is also effective in facilitating the excretion of uric acid.
There is quite a bit of scientific evidence that strongly suggests that acetic acid should help in the with uric acid elimination by raising the blood pH and increasing the solubility of uric acid. Acetate is also a vascular dilator which improves blood flow and dissolution of sodium urate crystals.
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12:58 pm June 23, 2009
| barabas
Gouty Twinges
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George Glasser said:
Actually, it isn't any magical properties in ACV, it's the plain old acetic acid that does the trick. Acetic acid is absorbed through the stomach as ionic acetate – not as an acid per-se – and oxidizes to a bicarbonate which raises the blood pH.
Potassium acetate is used for gout treatment. When it passes through the stomach lining into the blood, it converts to potassium carbonate, raises the blood pH and the alkaline salts excreted by the kidney render the urine less acid. “It is a marked diuretic, increasing the amount of urine and the solids of the urine without irritation of the kidney,” American Medical Association – “A Handbook of Usefu Drugs.”
Sodium acetate can also be used, but it causes stomach upset in some people – it would convert to bicarbonate of soda.
Potassium citrate is also effective in facilitating the excretion of uric acid.
There is quite a bit of scientific evidence that strongly suggests that acetic acid should help in the with uric acid elimination by raising the blood pH and increasing the solubility of uric acid. Acetate is also a vascular dilator which improves blood flow and dissolution of sodium urate crystals.
Sorry pals-will you share how one would take Apple cider vinegar,please
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4:40 pm June 23, 2009
| zip2play
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Post edited 9:48 pm – June 23, 2009 by zip2play
Salts like potassium acetate, sodium acetate, and potassium carbonate are salts formed from a weak acid and a strong base, I forget the name for these salts but when they are hydrolyzed the acidic part picks up and holds an H+ ion, taking it out of solution leaving an abundance of OH- to make the solution basic.
This CAN NOT be extended to the acid itself. Vinegar is ACID and thus it dissociates very differently from potassium acetate. It is actually Hydrogen acetate, or acetic acid and to the extent that it hydrolyzes it contributes substantial H+ ions into the solution (whereas the acetate SALTS contribute -OH (base) becasue of their K+ions. These are two VERY different situations.
One cannot assume the salt will have anything like the properties of the forming acids and bases. Thus while NaCl is delicious on food, it is quite a different effect from sprinkling the food with either lye (NaOh) or hydrochloric acid (HCl) which when mixed in a beaker make salt.
I've never measured the effect but I am sure that large amounts of acetic acid (vinegar) will acidify the urine but sodium or potassium acetate will alkalyze it.
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