Gout Research from Annals of the Rheumatic Diseases (ARD). 2008 Apr 2 [Epub ahead of print]
Aspiration of normal or asymptomatic pathological joints for diagnosis and research - indications, technique and success rate.
Pascual E, Doherty M.
Hospital General Universitario de Alicante, Spain.
Although joint aspiration is a basic clinical skill, aspiration of normal joints, or asymptomatic clinically quiescent joints, is only rarely undertaken.
There are two main indications for this procedure.
- for definitive diagnosis of crystal associated arthritis, both gout and pseudogout, during the intercritical period, and for subsequent monitoring of treatment success of gout
- to obtain normal synovial fluid for biomarker research.
The justification for these indications, the success rate, and the technical aspects related to this procedure are presented in this article.
PMID: 18385278 [PubMed - as supplied by publisher]