Gout Forum : Numbers Spiraling Upwards

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Numbers Spiraling Upwards

UserPost

1:37 pm
July 15, 2009


Tavery

Swollen Joints

Seattle Region

posts 70

A couple months of watching my diet and exercising more, my numbers were fairly steady when I tested myself. Recently my numbers started to rise and today I am having a significant flare-up in the usual big toe.

I havent been doing anything different diet-wise. I didnt go back to old habits. The only “cheating” I have done is I drank 4 Corona last Friday night (first beers in quite some time) and my chocolate intake and gone up a little bit (but not anywhere near as much as I used to eat).

I am very confused as to why my numbers have shot from an average of 5.7 to a 7.9 this morning.  Something like this…. 5.7, 5.6, 5.9, 5.8, 6.3, 6.7, 7.3, (yesterday) 7.9 (today). Yesterday morning I woke up to medium pain in my toe and this morning its hurts pretty good (enough that I am limping).

I want to understand why they would suddenly go up if I am avoiding all the “bad” foods like I have been.

Thoughts?


p.s. For the record, I contacted my doctor this morning about starting on Allopurinol because I obviously cant control this on my own through diet and exercise.

1:58 pm
July 15, 2009


trev

Tophi Terror

England

posts 809

I'm no expert , but I do think you'd be better off trying wine in place of beer. 2 small glasses only !

I did just what you did last month and ended up with an attack after 4 beers- I've just done 2 glasses of  wine and am sure I will not get an attack. A twinge maybe- if I exceed that low limit.

Giout never forgets how to get to you. Beer is double gout producing value versus wine.

Don't worry- I'm a bearded ex sailor with many kids and not bothered by being thought dodgy :)

I even do folk fests on occasions. They are better on beer, if you don't have microscopic needles waiting, that is!

On the back of this issue is the fact that there are imponderables with gout and being good doesn't always produce the required result -and being bad sometimes get an 'excused pass'.

3:07 pm
July 15, 2009


Tavery

Swollen Joints

Seattle Region

posts 70

If the beer is the cause, I dont think its good though that a four beers is enough to shove me so completely over the line into an attack after going so long with any beer. I thought I was making headway and it turns out I am just hovering under the threshold.

Sigh.

3:49 pm
July 15, 2009


trev

Tophi Terror

England

posts 809

Yeah- Stop -Go is not the way to handle gout, a lay off definitely makes for higher sensitivity for me.  You are hovering in a marginal zone with your UA readings.

I don't think it's the alcohol as such, though it doesn't help, it must be the yeast/purine element that does the 'little bit' extra!

The only other thing I can readily suggest is an old hangover preventative- drink a pint of water before retirng on a drinking session, it might just tip the balance in your favour!

1:56 pm
July 16, 2009


GoutPal

Admin

Baildon, Yorkshire

posts 1200

Tavery, don’t forget that most uric acid comes from our own natural metabolism. As old cells die, DNA is released, and becomes the raw material for uric acid. Anything that affects that process can boost the raw material available.

The enzyme, xanthine oxidase, is also required to cause the production of uric acid, which is why allopurinol is so effective, as it inhibits this process.

As well as eating habits, many other factors can affect both the rate at which our cells die, and the rate at which the resulting uric acid produces urate crystals.

It’s very easy to become food focused, but don’t forget that other factors might be the cause. It might be possible to isolate and eliminate these factors – if not, allopurinol is a good way to cut the worry.

Unless replying to specific points in this topic, please start a new topic. See new topic link above, or gout forum guidelines.
Current gout status in my profile.

1:11 pm
August 10, 2009


trev

Tophi Terror

England

posts 809

I know food [in gout] is given a lowish priority here and drug therapy preferred as a first line of attack.

Wiki, which I know is open source, does quote this:

The average uric acid level in men is 5.0 mg/dl, and substitution of a purine-free formula diet reduces this to 3.0 mg/dl. A purine-restricted diet lowers the level nearly as much (1–2 mg/dl).

Further, the critical level for a rise from 1% up to 22% getting gout occurs by their figures at a level of 9mg/dl. -quite high by standards here!

The figures do seem at odds to what passes here- but seem to allow much more latitude to UA levels as well as stressing the food element strongly. it would be helpful to know where these figures came from. I haven't risked even starting on the references listed.

 A good overview of the Gout topic, all the same. The above view does stand out.

http://en.wikipedia.org/wiki/Gout

6:20 am
November 18, 2009


trev

Tophi Terror

England

posts 809

I was looking into daily variations in SUA recently mentioned here by Nokka and , as often the case, I found other data that really tags on here.

http://rheumatology.oxfordjour…../1541/FIG1

[knock off the Fig1 for article link]

It shows the result of 35 healthy men sampled over a year. The average age was 35 and none obese.

The average SUA was just over 7mg/dL and very few sampled much under 6. This is quite a lot higher than the figure I quoted above and may explain why relatively high figures are considered normal .

Maybe they are- but not for established gouties!

10:23 am
November 18, 2009


zip2play

Member

posts 1278

I very much buy the higher numbers. I was startled to see the 5.0 for men, because none I know who are not on allopurinol have numbers that low..


(I have no clue on how to open that link or to get into the Oxford site…and I don't have Power Point!Surprised)

10:33 am
November 18, 2009


trev

Tophi Terror

England

posts 809

I 've seen 5+ quoted as normal in other reports, even today – so there are variations in sample groups.

These I quote now are not with gout- and that's the interesting bit.

I have noticed quite a few younger men posting here recently and it could be an age slanted effect is  in place with younger men at least getting gout more, due to unknown co -factors. [Sucrose intake?].

http://rheumatology.oxfordjour…..3/12/1541/


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