Newest Gout Treatment Is The Oldest
August 6, 2009 in Uncategorized
Turns out it is just our old friend colchicine, rebranded by URL Pharma.
This could be the biggest non-news gout story so far!
There is some benefit to gout sufferers – clearer dosage information. But fruit juice addicts need to be wary.
As part of the approval submission, URL Pharma have done dosage tests and conclude that lower doses than the “traditional” 4.8mg per day are just as effective. They suggest that 2 tablets (1.2mg) followed by a further .6mg tablet one hour later is the best dose.
The colchicine drug guide provides an extensive list of drugs that might interact with colchicine. Included in this list is grapefruit juice. Note that other potential CYP3A4 inhibitors include pomegranate, Seville oranges, pomello and star fruit.