GoutPal Interactive

This one is to allopurinol takers everywhere.

Every week, I get messages from gout sufferers, and their carers, about problems with allopurinol. Most of these show that absolutely no thought has gone into the treatment.

If you bought a car with only two wheels, would you accept it and drive round in a shower of sparks?
If you called a plumber to fix your leak, would you be happy to pay a weeks wages for him to merely turn the water off?
Would you pay an optician who grabbed the nearest pair of specs and said, “Here, these will do,” without testing your eyes?

Why take allopurinol without checking that it is doing it’s job?
Read the rest of this entry »

Somebody asked me the other day, “Can I stop taking allopurinol?”
The short answer is, “Maybe.”
Not very useful, so read on for the long answer.

First of all understand how allopurinol works.

It is all to do with uric acid. Uric acid is a good thing, but, when you have too much, it can form uric acid crystals (commonly called urate). These crystals build up in and around your joints causing gout. The only way to get rid of them is Read the rest of this entry »

You asked GoutPal about medication for gout.

The key thing to remember is that all gout medication falls into two groups:

• Pain Relief
• Urate Lowering Therapy

I have given full information about all common gout pain treatments and all common urate lowering therapies at GoutPal.com.

The most important of all medication for gout is treatment to lower uric acid. The most common, and currently most effective, urate lowering therapy is allopurinol. It is important that you study all the information about allopurinol on GoutPal.com.

When you start taking urate lowering medication, it is vital that you keep taking it every day. It does not matter if you are having a gout attack or not. Stopping the uric acid lowering treatment will not help the pain of that attack. If you stop taking it, you will increase the chances of more pain in future.

You need pain relief medication until the urate lowering therapy has done it’s job and all uric acid crystals have gone from your body. There is a wide choice available, and you should discuss different ones with your doctor. Do not put up with taking colchicine if it makes you sick. There are many alternatives, and you should be able to find one or two that suit you.

This post answers a short gout question in the gout cures section. If you need any more information about medication for gout please see my Gout Questions page.

Gouty Arthritis cures stop longterm gout. But how do you know they will work for you? Follow these guidelines to ensure you manage your gout properly

Looking for Allopurinol information to help your gout? Have you tried different spellings? Alipurinal, alipurinol, allipurinal, allopurino, alopurenol, or alopurinal are some alternative spellings that you might find. Got any more?

Gout pain relief is the first stage of gout management. The second stage is treatment to reduce uric acid, but this can cause more pain and many people miss this vital treatment because they cannot tolerate the pain. Recent discoveries regarding gout pain have suggested an alternative approach that may well lead to a new, more effective form of gout pain relief.

Many people mistakenly believe that uric acid crystals, commonly described as needle-like, cause pain in the same way that sticking pins in your body will. If you’ve studied my U-D-R-P model of gout pain, you will know that it is actually your immune system reacting to the crystals that causes swelling and pain in a similar way to fighting a virus. And the pain doesn’t only arise when something triggers these uric acid crystals to form.

A few days after your immune system has attacked uric acid crystals, swelling and pain subside as the crystals become hidden by white blood cells. But you need to reduce uric acid levels to get rid of gout, and whether you do this by diet or by drugs like allopurinol, those gout crystals that were hidden will become visible as they dissolve. This is why most doctors subscribe gout pain relief drugs such as colchicine or other anti-inflammatories (NSAIDS) at the same time as allopurinol. But many people simply cannot stomach these anti-inflammatory drugs and medical researchers are always on the look out for new approaches to gout pain relief.

Recent research into the immune system reaction to uric acid crystals has identified a protein called interleukin-1 (IL-1) as part of the problem. This has long been known to be a factor in rheumatoid arthritis, and a recent study, A Pilot Study of IL-1 Inhibition by Anakinra in Acute Gout, has treated gout patients with the rheumatoid arthritis drug, anakinra. Though this pilot study needs to be confirmed with randomized clinical trials, the authors conclude:

” In this pilot study involving 10 patients with gouty arthritis refractory to conventional therapies, anakinra given at 100 mg daily for 3 days rapidly relieved the inflammatory symptoms of gout. “

It’s good to see that deeper understanding of how gout pain is caused by the immune system has led to scientists looking for different types of treatment. It’s even better to see that applying existing drugs in new ways has led to a real possibility of a new, effective form of gout pain relief.

Rasburicase is very effective at lowering uric acid. Why isn’t it used for treating gout?