Uric Acid and Blood Pressure Medication
In fact, hypertension, high blood pressure, or diuretic in the Gout Search Engine (at the foot of every page, and elsewhere throughout the site) will reveal a wealth of information.
You might know that diuretics prescribed for high blood pressure are a common cause of gout. This need not be so.
With the right approach, it is actually possible to lower uric acid with blood pressure medication.
Back in May,
My research has shown one antihypertensive regimen that lowers uric acid. I will repeat it here.
It involves the use of two antihypertensive drugs, furosemide and losartan, (Lasix and Cozaar) but they must be taken in a particular way: first take the Lasix (which causes brisk diuresis) and then several hours later, take the Cozaar which causes uric acid elimination. Dosage of both drugs is titrated to get reasonable blood pressure control. Needless to say, people with NORMAL BP should not use this regimen.
The study confirming this regimen is small but rather convincing, but studies showing the uricosuric effect of losartan are all over the net. It;s the ONLY antihypertensive with this capability but used alone its effect is not large.
The name of the study is “Effects of the uricosuric action by losartan on the patients taking furosemide”, and the results show clearly in the chart above.
Furosemide alone raises uric acid on average by one third. If it is taken at the same time as losartan, then this increase is reduced to just over one fifth.
Losartan alone gives a slight reduction in uric acid, but as zip2play has pointed out in the gout forum, it is not especially effective at reducing high blood pressure. The correct procedure for gout sufferers with high blood pressure, as described by zip2play, is to take losartan a few hours after taking furosemide. The study shows that this can promote an average 15% drop in uric acid.
If you are not on this regime, discuss it with your doctor today. If you are, share your experience in the Gout Cure Forum.
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